<\/p>\n
<\/p>\n
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BMJ<\/em> 2023;383:e076321. Kaiser Permanente\u5317\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\uff0850\u6b73\u4ee5\u4e0a150\u4e07\u4eba\u30fb\u8ffd\u8de1\u671f\u95932007-2018\u5e74\uff09\u306e\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u30b3\u30db\u30fc\u30c8\u7814\u7a76\uff08Table 2\uff09<\/p>\n \u203b \u773c\u90e8\u5e2f\u72b6\u75b1\u75b9\u30fb\u5165\u9662\u306b\u3064\u3044\u3066\u306f\u3001\u75c7\u4f8b\u6570\u304c\u5c11\u306a\u3044\u305f\u3081\u671f\u9593\u3092\u307e\u3068\u3081\u305f\u96c6\u8a08\u5024\u3002\u300c\u2014\u300d\u306f\u5f53\u8a72\u671f\u9593\u3067\u306e\u7cbe\u5ea6\u5341\u5206\u306a\u63a8\u5b9a\u5024\u304c\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u533a\u9593\u3002<\/p>\n <\/p>\n \u2462 \u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\uff08\u7d44\u63db\u3048\u30ef\u30af\u30c1\u30f3\uff09\u5e74\u6b21\u5225\u4e88\u9632\u52b9\u679c\u306e\u63a8\u79fb<\/p>\n \u51fa\u5178\uff1aZOE-50\u30fbZOE-70\u8a66\u9a13\uff08\u63a5\u7a2e\u5f8c3\u301c4\u5e74\uff09\u3001ZOSTER-049\u9577\u671f\u8ffd\u8de1\u8a66\u9a13\uff08\u63a5\u7a2e\u5f8c5\u301c11\u5e74\uff09\u300210\u5e74\u3092\u8d85\u3048\u3066\u3082\u9ad8\u3044\u6709\u52b9\u6027\u3092\u7dad\u6301\u3002<\/p>\n <\/p>\n <\/p>\n 👨⚕️ \u9662\u9577\u307e\u3068\u3081<\/p>\n \u751f\u30ef\u30af\u30c1\u30f3\uff08\u30d3\u30b1\u30f3\uff09\u306f1\u56de\u63a5\u7a2e\u3067\u624b\u8efd\u3067\u3059\u304c\u3001\u4e0a\u8a18\u306e\u30c7\u30fc\u30bf\u304c\u793a\u3059\u3068\u304a\u308a\u3001\u63a5\u7a2e\u5f8c\u6570\u5e74\u3067\u52b9\u679c\u304c\u6025\u901f\u306b\u4f4e\u4e0b<\/strong>\u3057\u307e\u3059\uff0810\u5e74\u5f8c\u306b\u306f\u7d0415%\u307e\u3067\u4f4e\u4e0b\uff09\u3002 <\/p>\n ⚠️ \u3054\u6ce8\u610f<\/strong><\/p>\n <\/p>\n \u3054\u4e88\u7d04\u30fb\u304a\u554f\u3044\u5408\u308f\u305b<\/p>\n 📞 044-797-5556<\/strong>\uff08\u306a\u304b\u306f\u3089\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af\uff09 <\/p>\n 🏥 \u76e3\u4fee\u8005\u60c5\u5831<\/p>\n \u76e3\u4fee\uff1a\u5cb8 \u667a\uff08\u306a\u304b\u306f\u3089\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af \u9662\u9577\uff09<\/strong><\/p>\n \u306a\u304b\u306f\u3089\u5185\u79d1\u30af\u30ea\u30cb\u30c3\u30af<\/p>\n JR\u5357\u6b66\u7dda\u300c\u6b66\u8535\u4e2d\u539f\u99c5\u300d\u304b\u3089\u901a\u9662\u3057\u3084\u3059\u3044\u7acb\u5730\u306b\u3042\u308a\u3001\u6b66\u8535\u5c0f\u6749\u30fb\u5143\u4f4f\u5409\u30a8\u30ea\u30a2\u304b\u3089\u3082\u30a2\u30af\u30bb\u30b9\u826f\u597d\u3067\u3059\u3002 <\/p>\n \n \u3010\u51fa\u5178\u3011\u5ddd\u5d0e\u5e02\u300c\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u306e\u5b9a\u671f\u63a5\u7a2e\u300d\u30da\u30fc\u30b8\uff082026\u5e746\u670818\u65e5\u66f4\u65b0\uff09 <\/p>\n","protected":false},"excerpt":{"rendered":" 🛡️ \u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u5b9a\u671f\u63a5\u7a2e\u306e\u3054\u6848\u5185\uff08\u5ddd\u5d0e\u5e02\u30fb\u4ee4\u548c8\u5e74\u5ea6\uff09 \u5ddd\u5d0e\u5e02\u3067\u306f\u3001\u4ee4\u548c8\u5e74\uff082026\u5e74\uff094\u67081\u65e5\u3088\u308a\u9ad8\u9f62\u8005\u306e\u65b9\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u306e\u5b9a\u671f\u63a5\u7a2e\u304c\u59cb\u307e\u308a\u307e\u3057\u305f\u3002\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u306f\u5354\u529b … \u7d9a\u304d\u3092\u8aad\u3080 \u4ee4\u548c8\u5e74\u5ea6 \u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u5b9a\u671f\u63a5\u7a2e\u306e\u3054\u6848\u5185<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[2,14],"tags":[],"class_list":["post-3957","post","type-post","status-publish","format-standard","hentry","category-info","category-vaccination"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/posts\/3957","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/comments?post=3957"}],"version-history":[{"count":2,"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/posts\/3957\/revisions"}],"predecessor-version":[{"id":3959,"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/posts\/3957\/revisions\/3959"}],"wp:attachment":[{"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/media?parent=3957"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/categories?post=3957"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nakahara-naika.com\/blog\/wp-json\/wp\/v2\/tags?post=3957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}✅ \u5bfe\u8c61\u30fb\u5b9f\u65bd\u671f\u9593\u30fb\u81ea\u5df1\u8ca0\u62c5\u984d<\/h3>\n
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\n\n
\n \n\u30ef\u30af\u30c1\u30f3<\/th>\n \u56de\u6570<\/th>\n \u81ea\u5df1\u8ca0\u62c5\u984d<\/th>\n \u9662\u9577\u8a55\u4fa1<\/th>\n<\/tr>\n<\/thead>\n \n \u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9<\/strong>\uff08\u7d44\u63db\u3048\u30ef\u30af\u30c1\u30f3\uff09<\/td>\n 2\u56de
2\u304b\u6708\u4ee5\u4e0a\u306e\u9593\u9694<\/span><\/td>\n10,000\u5186\u00d72\u56de<\/strong>
\u5408\u8a0820,000\u5186\uff08\u7a0e\u8fbc\uff09<\/td>\n⭐ \u9662\u9577\u304a\u3059\u3059\u3081<\/strong><\/td>\n<\/tr>\n \n \u751f\u30ef\u30af\u30c1\u30f3\uff08\u30d3\u30b1\u30f3\uff09<\/td>\n 1\u56de<\/td>\n 4,000\u5186<\/strong>\uff08\u7a0e\u8fbc\uff09<\/td>\n \u9078\u629e\u53ef<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<\/p><\/div>\n \n
📊 \u30ef\u30af\u30c1\u30f3\u6709\u52b9\u6027\u30c7\u30fc\u30bf\u6bd4\u8f03<\/h3>\n<\/p><\/div>\n
\n
\n \n\u4e88\u9632\u52b9\u679c<\/th>\n 🔵 \u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\uff08\u7d44\u63db\u3048\u30ef\u30af\u30c1\u30f3\uff09<\/th>\n ⬜ \u751f\u30ef\u30af\u30c1\u30f3\uff08\u30d3\u30b1\u30f3\uff09<\/th>\n<\/tr>\n<\/thead>\n \n \u5e2f\u72b6\u75b1\u75b9
\u767a\u75c7\u4e88\u9632<\/td>\n\n 97.2%<\/span>
\n 50\u6b73\u4ee5\u4e0a\u30fbZOE-50\u8a66\u9a13<\/span>
\n 91.3%<\/span>
\n 70\u6b73\u4ee5\u4e0a\u30fbZOE-70\u8a66\u9a13<\/span>\n <\/td>\n\n 45.7%<\/span>
\n \u89b3\u5bdf\u671f\u9593\u5168\u4f53<\/span>\n <\/td>\n<\/tr>\n\n \u5e2f\u72b6\u75b1\u75b9\u5f8c
\u795e\u7d4c\u75db\uff08PHN\uff09
\u4e88\u9632<\/td>\n\n 91.2%<\/span>
\n ZOE-50\u8a66\u9a13<\/span>
\n 88.8%<\/span>
\n 70\u6b73\u4ee5\u4e0a\u30fbZOE-70\u8a66\u9a13<\/span>\n <\/td>\n\n 62.3%<\/span>
\n \u89b3\u5bdf\u671f\u9593\u5168\u4f53<\/span>\n <\/td>\n<\/tr>\n\n \u773c\u90e8\u5e2f\u72b6\u75b1\u75b9
\u4e88\u9632<\/td>\n\n \u301c90%\u4ee5\u4e0a<\/span>
\n ZOE\u8a66\u9a13\u306b\u304a\u3051\u308b
\u5408\u4f75\u75c7\u5168\u4f53\u306e\u9ad8\u3044\u6709\u52b9\u6027\u3088\u308a\u63a8\u5b9a<\/span>\n <\/td>\n\n 44.5%<\/span>
\n \u89b3\u5bdf\u671f\u9593\u5168\u4f53<\/span>\n <\/td>\n<\/tr>\n\n \u5e2f\u72b6\u75b1\u75b9\u306b\u3088\u308b
\u5165\u9662\u4e88\u9632<\/td>\n\n \u301c90%\u4ee5\u4e0a<\/span>
\n \u9ad8\u3044\u767a\u75c7\u4e88\u9632\u7387\u306b\u3088\u308a
\u91cd\u75c7\u5316\u30fb\u5165\u9662\u3092\u5927\u5e45\u6291\u5236<\/span>\n <\/td>\n\n 65.9%<\/span>
\n \u89b3\u5bdf\u671f\u9593\u5168\u4f53<\/span>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n
\n \n\u63a5\u7a2e\u5f8c\u306e\u671f\u9593<\/th>\n \u5e2f\u72b6\u75b1\u75b9
\u767a\u75c7\u4e88\u9632<\/th>\nPHN\u4e88\u9632
\uff08\u5e2f\u72b6\u75b1\u75b9\u5f8c\u795e\u7d4c\u75db\uff09<\/th>\n\u773c\u90e8
\u5e2f\u72b6\u75b1\u75b9\u4e88\u9632<\/th>\n\u5e2f\u72b6\u75b1\u75b9\u306b\u3088\u308b
\u5165\u9662\u4e88\u9632<\/th>\n<\/tr>\n<\/thead>\n\n \u301c1\u5e74\u76ee<\/td>\n 67.2%<\/td>\n 83.0%<\/td>\n 70.6%<\/td>\n 89.5%<\/td>\n<\/tr>\n \n 1\u301c2\u5e74\u76ee<\/td>\n 49.6%<\/td>\n 64.6%<\/td>\n 48.1%<\/td>\n 69.6%<\/td>\n<\/tr>\n \n 2\u301c3\u5e74\u76ee<\/td>\n 42.0%<\/td>\n \uff083\u301c5\u5e74\u76ee\u3067\u96c6\u8a08\uff09<\/td>\n \uff083\u301c5\u5e74\u76ee\u3067\u96c6\u8a08\uff09<\/td>\n \uff083\u301c5\u5e74\u76ee\u3067\u96c6\u8a08\uff09<\/td>\n<\/tr>\n \n 3\u301c5\u5e74\u76ee<\/td>\n 39.9%
\uff083\u301c4\u5e74\u76ee\uff09<\/span>
37.0%
\uff084\u301c5\u5e74\u76ee\uff09<\/span><\/td>\n58.0%<\/td>\n 32.4%<\/td>\n 69.8%<\/td>\n<\/tr>\n \n 5\u301c6\u5e74\u76ee<\/td>\n 33.5%<\/td>\n \uff085\u301c8\u5e74\u76ee\u3067\u96c6\u8a08\uff09<\/td>\n \uff085\u301c8\u5e74\u76ee\u3067\u96c6\u8a08\uff09<\/td>\n \uff085\u301c8\u5e74\u76ee\u3067\u96c6\u8a08\uff09<\/td>\n<\/tr>\n \n 6\u301c7\u5e74\u76ee<\/td>\n 27.3%<\/td>\n \u2193<\/td>\n \u2193<\/td>\n \u2193<\/td>\n<\/tr>\n \n 5\u301c8\u5e74\u76ee
(\u773c\u90e8\u30fb\u5165\u9662\u96c6\u8a08)<\/span><\/td>\n\uff08\u5404\u5e74\u5225\u306b\u5de6\u5217\u53c2\u7167\uff09<\/td>\n \uff08\u4e0b\u8a18\u96c6\u8a08\u5024\u53c2\u7167\uff09<\/td>\n 29.4%<\/strong><\/td>\n 52.5%<\/strong><\/td>\n<\/tr>\n \n 7\u301c8\u5e74\u76ee<\/td>\n 26.9%<\/td>\n \u2193<\/td>\n \uff08\u7cbe\u5ea6\u4e0d\u5341\u5206\uff09<\/td>\n \uff08\u7cbe\u5ea6\u4e0d\u5341\u5206\uff09<\/td>\n<\/tr>\n \n 8\u301c9\u5e74\u76ee<\/td>\n 25.1%<\/td>\n 46.4%<\/td>\n 12.4%<\/strong>
\uff088\u301c10\u5e74\u76ee\u96c6\u8a08\uff09<\/span><\/td>\n42.8%<\/strong>
\uff088\u301c10\u5e74\u76ee\u96c6\u8a08\uff09<\/span><\/td>\n<\/tr>\n\n 9\u301c10\u5e74\u76ee<\/td>\n 19.1%<\/strong><\/td>\n \uff08\u4e0b\u8a18\u96c6\u8a08\u5024\u53c2\u7167\uff09<\/td>\n \u2014<\/td>\n \u2014<\/td>\n<\/tr>\n \n 10\u301c12\u5e74\u76ee<\/td>\n 14.9%<\/strong><\/td>\n 41.4%<\/strong><\/td>\n \u7cbe\u5ea6\u4e0d\u5341\u5206<\/td>\n \u7cbe\u5ea6\u4e0d\u5341\u5206<\/td>\n<\/tr>\n \n \u89b3\u5bdf\u671f\u9593\u5168\u4f53
\uff08Overall VE\uff09<\/td>\n45.7%<\/td>\n 62.3%<\/td>\n 44.5%<\/td>\n 65.9%<\/td>\n<\/tr>\n \n 10\u5e74\u9593\u5e73\u5747
\uff08Average VE\uff09<\/td>\n38.1%<\/td>\n 59.0%<\/td>\n 36.6%<\/td>\n 64.2%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n \n
\n \n\u63a5\u7a2e\u5f8c\u306e\u671f\u9593<\/th>\n \u5e2f\u72b6\u75b1\u75b9 \u767a\u75c7\u4e88\u9632<\/th>\n PHN\u4e88\u9632<\/th>\n<\/tr>\n<\/thead>\n \n 1\u301c3\u5e74\u76ee<\/td>\n 97.2%<\/strong>
\uff08ZOE-50\u8a66\u9a13\u30fb50\u6b73\u4ee5\u4e0a\uff09<\/span><\/td>\n91.2%<\/strong>
\uff08ZOE-50\u8a66\u9a13\uff09<\/span><\/td>\n<\/tr>\n\n 3\u301c4\u5e74\u76ee<\/td>\n 91.3%<\/strong>
\uff08ZOE-70\u8a66\u9a13\u30fb70\u6b73\u4ee5\u4e0a\uff09<\/span><\/td>\n88.8%<\/strong>
\uff08ZOE-70\u8a66\u9a13\u30fb70\u6b73\u4ee5\u4e0a\uff09<\/span><\/td>\n<\/tr>\n\n 5\u301c10\u5e74\u76ee<\/td>\n \u301c90%\u524d\u5f8c<\/strong>
\uff08ZOSTER-049\u8a66\u9a13\uff09<\/span><\/td>\n\u9ad8\u3044\u4e88\u9632\u52b9\u679c\u3092\u7dad\u6301
\uff08\u8a66\u9a13\u7d99\u7d9a\u4e2d\uff09<\/span><\/td>\n<\/tr>\n\n \u63a5\u7a2e\u5f8c11\u5e74\u76ee
\uff08\u9577\u671f\u901a\u7b97\uff09<\/td>\n87.7%<\/strong>
\uff08ZOE-LTFU\u6700\u7d42\u89e3\u6790\u30fb\u63a5\u7a2e\u5f8c11.4\u5e74\u9593\u901a\u7b97\uff09<\/span><\/td>\nZOSTER-049\u8a66\u9a13\u671f\u9593\u4e2d\u306ePHN\u767a\u75c7\uff1a
\u30ef\u30af\u30c1\u30f3\u7fa4 4\u4f8b vs \u5bfe\u7167\u7fa4 32\u4f8b<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n \u4e00\u65b9\u3001\u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\u306f\u63a5\u7a2e\u5f8c11\u5e74\u3092\u7d4c\u904e\u3057\u305f\u5f8c\u3082\u7d0488%\u306e\u9ad8\u3044\u6709\u52b9\u6027<\/strong>\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u304c\u5927\u898f\u6a21\u9577\u671f\u8a66\u9a13\uff08ZOE-LTFU\u6700\u7d42\u89e3\u6790\uff09\u3067\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n \u5e2f\u72b6\u75b1\u75b9\u306e\u767a\u75c7\u30fb\u5f8c\u907a\u75c7\uff08\u795e\u7d4c\u75db\uff09\u30fb\u91cd\u75c7\u5316\u3092\u3057\u3063\u304b\u308a\u9632\u304e\u305f\u3044\u65b9\u306b\u306f\u3001\u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\u3092\u5f37\u304f\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/strong>\u307e\u305a\u306f\u304a\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/p><\/div>\n\n
\n \u307e\u305f\u306f WEB\u4e88\u7d04\u3088\u308a\u304a\u7533\u3057\u8fbc\u307f\u304f\u3060\u3055\u3044<\/span><\/p>\n<\/p><\/div>\n\n
\n \u5ddd\u5d0e\u5e02\u4e2d\u539f\u533a\u3092\u4e2d\u5fc3\u306b\u3001\u6b66\u8535\u5c0f\u6749\u30fb\u5143\u4f4f\u5409\u30fb\u65e5\u5409\u30fb\u6b66\u8535\u65b0\u57ce\u30a8\u30ea\u30a2\u306a\u3069\u3001\u5e45\u5e83\u3044\u5730\u57df\u306e\u60a3\u8005\u69d8\u306b\u3054\u6765\u9662\u3044\u305f\u3060\u3044\u3066\u304a\u308a\u307e\u3059\u3002
\n \u5185\u79d1\u5168\u822c\u306b\u52a0\u3048\u3001\u9ad8\u8840\u5727\u30fb\u7cd6\u5c3f\u75c5\u30fb\u8102\u8cea\u7570\u5e38\u75c7\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u3001\u52d5\u60b8\u30fb\u80f8\u75db\u306a\u3069\u5faa\u74b0\u5668\u75be\u60a3\u306e\u8a3a\u7642\u306b\u3082\u5bfe\u5fdc\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n<\/p><\/div>\n
\n \u751f\u30ef\u30af\u30c1\u30f3\uff1aKlein NP, et al. Effectiveness of the live zoster vaccine during the 10 years following vaccination: real world cohort study using electronic health records. BMJ<\/em> 2023;383:e076321. doi:10.1136\/bmj-2023-076321
\n \u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\uff1aLal H, et al. ZOE-50\u8a66\u9a13 (N Engl J Med<\/em> 2015;372:2087)\uff1bCunningham AL, et al. ZOE-70\u8a66\u9a13 (N Engl J Med<\/em> 2016;375:1019)\uff1bStrezova A, et al. ZOE-LTFU\u6700\u7d42\u89e3\u6790 (eClinicalMedicine<\/em> 2025;83:103241)\n <\/p>\n<\/div>\n